Cargando…
A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery
CONTEXT: Adjuvants to bupivacaine for single shot caudal block in children. AIMS: This study entitled was conducted to compare the effects of addition of tramadol to bupivacaine over addition of clonidine to bupivacaine as a single shot caudal block in children. SETTINGS AND DESIGN: Sixty children o...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545941/ https://www.ncbi.nlm.nih.gov/pubmed/31198265 http://dx.doi.org/10.4103/aer.AER_37_19 |
_version_ | 1783423468454281216 |
---|---|
author | Amitha, S Metri, Vidyadhar Mahadevaiah, Thejeswini Yoganarasimha, |
author_facet | Amitha, S Metri, Vidyadhar Mahadevaiah, Thejeswini Yoganarasimha, |
author_sort | Amitha, S |
collection | PubMed |
description | CONTEXT: Adjuvants to bupivacaine for single shot caudal block in children. AIMS: This study entitled was conducted to compare the effects of addition of tramadol to bupivacaine over addition of clonidine to bupivacaine as a single shot caudal block in children. SETTINGS AND DESIGN: Sixty children of ASA grade I and II in the age group of 2-12 years coming for various infra-umbilical surgeries were included. MATERIALS AND METHODS: They were divided into two groups of 30 each. Group BC received caudal bupivacaine 0.25% 0.5ml/kg with clonidine 2 mcg/kg Group BT received caudal bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg. The main parameters studied were hemodynamic changes, duration of post-operative analgesia and incidence of adverse effects. STATISTICAL ANALYSIS USED: The results of continuous variables are given as mean ± SD and proportion as percentage. The difference between the two groups was assessed by student's – t test and chi-square test RESULTS: The mean duration of post-operative analgesia in group BT was statistically significant (P <0.001), reducing the requirement of analgesics in group BT. There was no difference in sedation score, nausea, vomiting, urinary retention. CONCLUSIONS: The present study demonstrated that caudal administration of bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg resulted in superior analgesia with longer duration of action and reduced requirement of analgesics in first 24 hours postoperatively when compared with 0.25% bupivacaine 0.5 ml/kg with clonidine 2 mcg/kg. |
format | Online Article Text |
id | pubmed-6545941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65459412019-06-13 A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery Amitha, S Metri, Vidyadhar Mahadevaiah, Thejeswini Yoganarasimha, Anesth Essays Res Original Article CONTEXT: Adjuvants to bupivacaine for single shot caudal block in children. AIMS: This study entitled was conducted to compare the effects of addition of tramadol to bupivacaine over addition of clonidine to bupivacaine as a single shot caudal block in children. SETTINGS AND DESIGN: Sixty children of ASA grade I and II in the age group of 2-12 years coming for various infra-umbilical surgeries were included. MATERIALS AND METHODS: They were divided into two groups of 30 each. Group BC received caudal bupivacaine 0.25% 0.5ml/kg with clonidine 2 mcg/kg Group BT received caudal bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg. The main parameters studied were hemodynamic changes, duration of post-operative analgesia and incidence of adverse effects. STATISTICAL ANALYSIS USED: The results of continuous variables are given as mean ± SD and proportion as percentage. The difference between the two groups was assessed by student's – t test and chi-square test RESULTS: The mean duration of post-operative analgesia in group BT was statistically significant (P <0.001), reducing the requirement of analgesics in group BT. There was no difference in sedation score, nausea, vomiting, urinary retention. CONCLUSIONS: The present study demonstrated that caudal administration of bupivacaine 0.25% 0.5 ml/kg with tramadol 2 mg/kg resulted in superior analgesia with longer duration of action and reduced requirement of analgesics in first 24 hours postoperatively when compared with 0.25% bupivacaine 0.5 ml/kg with clonidine 2 mcg/kg. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6545941/ /pubmed/31198265 http://dx.doi.org/10.4103/aer.AER_37_19 Text en Copyright: © 2019 Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Amitha, S Metri, Vidyadhar Mahadevaiah, Thejeswini Yoganarasimha, A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title | A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title_full | A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title_fullStr | A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title_full_unstemmed | A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title_short | A Comparative Clinical Study between Clonidine and Tramadol with Bupivacaine in Caudal Epidural for Postoperative Analgesia in Pediatric Surgery |
title_sort | comparative clinical study between clonidine and tramadol with bupivacaine in caudal epidural for postoperative analgesia in pediatric surgery |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545941/ https://www.ncbi.nlm.nih.gov/pubmed/31198265 http://dx.doi.org/10.4103/aer.AER_37_19 |
work_keys_str_mv | AT amithas acomparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT metrividyadhar acomparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT mahadevaiahthejeswini acomparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT yoganarasimha acomparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT amithas comparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT metrividyadhar comparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT mahadevaiahthejeswini comparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery AT yoganarasimha comparativeclinicalstudybetweenclonidineandtramadolwithbupivacaineincaudalepiduralforpostoperativeanalgesiainpediatricsurgery |