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Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction
BACKGROUND: Postoperative pulmonary dysfunction is a prevalent complication after cardiac surgery; it has many contributing considerations due to either the surgery itself, anomalies to gas exchange or maybe as a result of alterations in lung mechanics. The aim of this study was to compare pressure-...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545959/ https://www.ncbi.nlm.nih.gov/pubmed/31198237 http://dx.doi.org/10.4103/aer.AER_48_19 |
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author | Hussain, Noha Sayed Metry, Ayman Anis Nakhla, George Mikhail Wahba, Rami Mounir Ragaei, Milad Zakery Bestarous, John Nader |
author_facet | Hussain, Noha Sayed Metry, Ayman Anis Nakhla, George Mikhail Wahba, Rami Mounir Ragaei, Milad Zakery Bestarous, John Nader |
author_sort | Hussain, Noha Sayed |
collection | PubMed |
description | BACKGROUND: Postoperative pulmonary dysfunction is a prevalent complication after cardiac surgery; it has many contributing considerations due to either the surgery itself, anomalies to gas exchange or maybe as a result of alterations in lung mechanics. The aim of this study was to compare pressure-controlled ventilation versus volume-controlled ventilation in the presence of no ventilation group as a control group during cardiopulmonary bypass and its effect on postoperative pulmonary dysfunction. PATIENTS AND METHODS: Sixty-six patients going through open-heart surgeries were included in the study. They divided into three groups (Group P: Pressure-controlled ventilation, Group V: Volume-controlled ventilation, and Group C: Control group with no ventilation) in accordance with the mode of ventilation. Patients studied for chest X-ray, lung ultrasound, arterial oxygen partial pressure to fractional inspired oxygen ratio, alveolar–arterial oxygen gradient, static lung compliance, and dynamic lung compliance, taken after induction of anesthesia, 1-h post-CPB, and 1 h after arrival to cardiac surgical unit. RESULTS: There was no significant difference regarding the chest X-ray and lung ultrasonography results among the three groups of the study. Regarding arterial oxygen partial pressure to fractional inspired oxygen ratio, alveolar–arterial oxygen gradient, static lung compliance, and dynamic lung compliance, the results showed lower values in the postbypass period, and the postoperative period compared to the postinduction period among the three groups of the study with no significant difference. CONCLUSIONS: The evidence of clear benefits of maintaining ventilation alone during cardiopulmonary bypass is inconsistent. More studies are required to determine the precise role of different lung protective strategies during cardiopulmonary bypass. |
format | Online Article Text |
id | pubmed-6545959 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-65459592019-06-13 Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction Hussain, Noha Sayed Metry, Ayman Anis Nakhla, George Mikhail Wahba, Rami Mounir Ragaei, Milad Zakery Bestarous, John Nader Anesth Essays Res Original Article BACKGROUND: Postoperative pulmonary dysfunction is a prevalent complication after cardiac surgery; it has many contributing considerations due to either the surgery itself, anomalies to gas exchange or maybe as a result of alterations in lung mechanics. The aim of this study was to compare pressure-controlled ventilation versus volume-controlled ventilation in the presence of no ventilation group as a control group during cardiopulmonary bypass and its effect on postoperative pulmonary dysfunction. PATIENTS AND METHODS: Sixty-six patients going through open-heart surgeries were included in the study. They divided into three groups (Group P: Pressure-controlled ventilation, Group V: Volume-controlled ventilation, and Group C: Control group with no ventilation) in accordance with the mode of ventilation. Patients studied for chest X-ray, lung ultrasound, arterial oxygen partial pressure to fractional inspired oxygen ratio, alveolar–arterial oxygen gradient, static lung compliance, and dynamic lung compliance, taken after induction of anesthesia, 1-h post-CPB, and 1 h after arrival to cardiac surgical unit. RESULTS: There was no significant difference regarding the chest X-ray and lung ultrasonography results among the three groups of the study. Regarding arterial oxygen partial pressure to fractional inspired oxygen ratio, alveolar–arterial oxygen gradient, static lung compliance, and dynamic lung compliance, the results showed lower values in the postbypass period, and the postoperative period compared to the postinduction period among the three groups of the study with no significant difference. CONCLUSIONS: The evidence of clear benefits of maintaining ventilation alone during cardiopulmonary bypass is inconsistent. More studies are required to determine the precise role of different lung protective strategies during cardiopulmonary bypass. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6545959/ /pubmed/31198237 http://dx.doi.org/10.4103/aer.AER_48_19 Text en Copyright: © 2019 Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Hussain, Noha Sayed Metry, Ayman Anis Nakhla, George Mikhail Wahba, Rami Mounir Ragaei, Milad Zakery Bestarous, John Nader Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title | Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title_full | Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title_fullStr | Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title_full_unstemmed | Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title_short | Comparative Study between Different Modes of Ventilation during Cardiopulmonary Bypass and its Effect on Postoperative Pulmonary Dysfunction |
title_sort | comparative study between different modes of ventilation during cardiopulmonary bypass and its effect on postoperative pulmonary dysfunction |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545959/ https://www.ncbi.nlm.nih.gov/pubmed/31198237 http://dx.doi.org/10.4103/aer.AER_48_19 |
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