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Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment

Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcathete...

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Autores principales: Curio, Jonathan, Demir, Ozan M, Pagnesi, Matteo, Mangieri, Antonio, Giannini, Francesco, Weisz, Giora, Latib, Azeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545971/
https://www.ncbi.nlm.nih.gov/pubmed/31178930
http://dx.doi.org/10.15420/icr.2019.5.1
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author Curio, Jonathan
Demir, Ozan M
Pagnesi, Matteo
Mangieri, Antonio
Giannini, Francesco
Weisz, Giora
Latib, Azeem
author_facet Curio, Jonathan
Demir, Ozan M
Pagnesi, Matteo
Mangieri, Antonio
Giannini, Francesco
Weisz, Giora
Latib, Azeem
author_sort Curio, Jonathan
collection PubMed
description Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcatheter tricuspid regurgitation treatment including different approaches (i.e. repair with leaflet approximation or annuloplasty and replacement using orthotopic or heterotopic valves) at different stages of development, from experimental to clinical trial. Repair devices such as the Cardioband or the MitraClip are leading the field with promising preliminary data and further trials are ongoing. However, with implantations of the Gate bioprosthesis, replacement devices are catching up. Potential advantages of different approaches and most recent data are discussed.
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spelling pubmed-65459712019-06-07 Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment Curio, Jonathan Demir, Ozan M Pagnesi, Matteo Mangieri, Antonio Giannini, Francesco Weisz, Giora Latib, Azeem Interv Cardiol Structural Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcatheter tricuspid regurgitation treatment including different approaches (i.e. repair with leaflet approximation or annuloplasty and replacement using orthotopic or heterotopic valves) at different stages of development, from experimental to clinical trial. Repair devices such as the Cardioband or the MitraClip are leading the field with promising preliminary data and further trials are ongoing. However, with implantations of the Gate bioprosthesis, replacement devices are catching up. Potential advantages of different approaches and most recent data are discussed. Radcliffe Cardiology 2019-05-21 /pmc/articles/PMC6545971/ /pubmed/31178930 http://dx.doi.org/10.15420/icr.2019.5.1 Text en Copyright © 2019, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/legalcode This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Structural
Curio, Jonathan
Demir, Ozan M
Pagnesi, Matteo
Mangieri, Antonio
Giannini, Francesco
Weisz, Giora
Latib, Azeem
Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title_full Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title_fullStr Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title_full_unstemmed Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title_short Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
title_sort update on the current landscape of transcatheter options for tricuspid regurgitation treatment
topic Structural
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545971/
https://www.ncbi.nlm.nih.gov/pubmed/31178930
http://dx.doi.org/10.15420/icr.2019.5.1
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