Cargando…
Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment
Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcathete...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Radcliffe Cardiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545971/ https://www.ncbi.nlm.nih.gov/pubmed/31178930 http://dx.doi.org/10.15420/icr.2019.5.1 |
_version_ | 1783423475562577920 |
---|---|
author | Curio, Jonathan Demir, Ozan M Pagnesi, Matteo Mangieri, Antonio Giannini, Francesco Weisz, Giora Latib, Azeem |
author_facet | Curio, Jonathan Demir, Ozan M Pagnesi, Matteo Mangieri, Antonio Giannini, Francesco Weisz, Giora Latib, Azeem |
author_sort | Curio, Jonathan |
collection | PubMed |
description | Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcatheter tricuspid regurgitation treatment including different approaches (i.e. repair with leaflet approximation or annuloplasty and replacement using orthotopic or heterotopic valves) at different stages of development, from experimental to clinical trial. Repair devices such as the Cardioband or the MitraClip are leading the field with promising preliminary data and further trials are ongoing. However, with implantations of the Gate bioprosthesis, replacement devices are catching up. Potential advantages of different approaches and most recent data are discussed. |
format | Online Article Text |
id | pubmed-6545971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Radcliffe Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-65459712019-06-07 Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment Curio, Jonathan Demir, Ozan M Pagnesi, Matteo Mangieri, Antonio Giannini, Francesco Weisz, Giora Latib, Azeem Interv Cardiol Structural Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcatheter tricuspid regurgitation treatment including different approaches (i.e. repair with leaflet approximation or annuloplasty and replacement using orthotopic or heterotopic valves) at different stages of development, from experimental to clinical trial. Repair devices such as the Cardioband or the MitraClip are leading the field with promising preliminary data and further trials are ongoing. However, with implantations of the Gate bioprosthesis, replacement devices are catching up. Potential advantages of different approaches and most recent data are discussed. Radcliffe Cardiology 2019-05-21 /pmc/articles/PMC6545971/ /pubmed/31178930 http://dx.doi.org/10.15420/icr.2019.5.1 Text en Copyright © 2019, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/legalcode This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly. |
spellingShingle | Structural Curio, Jonathan Demir, Ozan M Pagnesi, Matteo Mangieri, Antonio Giannini, Francesco Weisz, Giora Latib, Azeem Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title | Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title_full | Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title_fullStr | Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title_full_unstemmed | Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title_short | Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment |
title_sort | update on the current landscape of transcatheter options for tricuspid regurgitation treatment |
topic | Structural |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545971/ https://www.ncbi.nlm.nih.gov/pubmed/31178930 http://dx.doi.org/10.15420/icr.2019.5.1 |
work_keys_str_mv | AT curiojonathan updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT demirozanm updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT pagnesimatteo updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT mangieriantonio updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT gianninifrancesco updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT weiszgiora updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment AT latibazeem updateonthecurrentlandscapeoftranscatheteroptionsfortricuspidregurgitationtreatment |