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The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells
The transcriptional repression of alternative lineage genes is critical for cell fate commitment. Mechanisms by which locus-specific gene silencing is initiated and heritably maintained during cell division are not clearly understood. To study the maintenance of silent gene states, we investigated h...
Autores principales: | Ng, Charles, Aichinger, Martin, Nguyen, Tung, Au, Christy, Najar, Tariq, Wu, Lin, Mesa, Kai R., Liao, Will, Quivy, Jean-Pierre, Hubert, Benjamin, Almouzni, Genevieve, Zuber, Johannes, Littman, Dan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546056/ https://www.ncbi.nlm.nih.gov/pubmed/30975723 http://dx.doi.org/10.1101/gad.322024.118 |
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