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The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells

The transcriptional repression of alternative lineage genes is critical for cell fate commitment. Mechanisms by which locus-specific gene silencing is initiated and heritably maintained during cell division are not clearly understood. To study the maintenance of silent gene states, we investigated h...

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Detalles Bibliográficos
Autores principales: Ng, Charles, Aichinger, Martin, Nguyen, Tung, Au, Christy, Najar, Tariq, Wu, Lin, Mesa, Kai R., Liao, Will, Quivy, Jean-Pierre, Hubert, Benjamin, Almouzni, Genevieve, Zuber, Johannes, Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546056/
https://www.ncbi.nlm.nih.gov/pubmed/30975723
http://dx.doi.org/10.1101/gad.322024.118

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