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The long noncoding RNA Falcor regulates Foxa2 expression to maintain lung epithelial homeostasis and promote regeneration

Transcription factors (TFs) are dosage-sensitive master regulators of gene expression, with haploinsufficiency frequently leading to life-threatening disease. Numerous mechanisms have evolved to tightly regulate the expression and activity of TFs at the transcriptional, translational, and posttransl...

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Detalles Bibliográficos
Autores principales: Swarr, Daniel T., Herriges, Michael, Li, Shanru, Morley, Mike, Fernandes, Sharlene, Sridharan, Anusha, Zhou, Su, Garcia, Benjamin A., Stewart, Kathleen, Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546060/
https://www.ncbi.nlm.nih.gov/pubmed/30923168
http://dx.doi.org/10.1101/gad.320523.118