High-complexity regions in mammalian genomes are enriched for developmental genes

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MOTIVATION: Unique sequence regions are associated with genetic function in vertebrate genomes. However, measuring uniqueness, or absence of long repeats, along a genome is conceptually and computationally difficult. Here we use a variant of the Lempel-Ziv complexity, the match complexity, [Formula:...

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Detalles Bibliográficos
Autores principales: Pirogov, Anton, Pfaffelhuber, Peter, Börsch-Haubold, Angelika, Haubold, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546125/
https://www.ncbi.nlm.nih.gov/pubmed/30395202
http://dx.doi.org/10.1093/bioinformatics/bty922

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