Statistical inference of the rate of RNA polymerase II elongation by total RNA sequencing

MOTIVATION: Sequencing total RNA without poly-A selection enables us to obtain a transcriptomic profile of nascent RNAs undergoing transcription with co-transcriptional splicing. In general, the RNA-seq reads exhibit a sawtooth pattern in a gene, which is characterized by a monotonically decreasing...

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Detalles Bibliográficos
Autores principales: Kawamura, Yumi, Koyama, Shinsuke, Yoshida, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546130/
https://www.ncbi.nlm.nih.gov/pubmed/30376061
http://dx.doi.org/10.1093/bioinformatics/bty886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546130/
https://www.ncbi.nlm.nih.gov/pubmed/30376061
http://dx.doi.org/10.1093/bioinformatics/bty886

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