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simGWAS: a fast method for simulation of large scale case–control GWAS summary statistics

MOTIVATION: Methods for analysis of GWAS summary statistics have encouraged data sharing and democratized the analysis of different diseases. Ideal validation for such methods is application to simulated data, where some ‘truth’ is known. As GWAS increase in size, so does the computational complexit...

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Detalles Bibliográficos
Autores principales: Fortune, Mary D, Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546134/
https://www.ncbi.nlm.nih.gov/pubmed/30371734
http://dx.doi.org/10.1093/bioinformatics/bty898