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Dolutegravir Cerebrospinal Fluid Diffusion in HIV-1–Infected Patients with Central Nervous System Impairment

This study aimed to determine dolutegravir cerebrospinal fluid (CSF) diffusion in 13 patients with HIV-related cerebral impairment enrolled in a real-life observational study. Dolutegravir median (range) CSF concentration [9.6 (3.6–22.8) ng/mL] reached CSF therapeutic concentrations whatever the blo...

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Detalles Bibliográficos
Autores principales: Gelé, Thibaut, Furlan, Valérie, Taburet, Anne-Marie, Pallier, Coralie, Becker, Pierre-Hadrien, Goujard, Cécile, Gasnault, Jacques, Barrail-Tran, Aurélie, Chéret, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546201/
https://www.ncbi.nlm.nih.gov/pubmed/31198814
http://dx.doi.org/10.1093/ofid/ofz174