Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition

The clinical significance of BRAF alterations in well-differentiated (WD) metastatic pancreatic neuroendocrine tumor (panNET) is unknown, but BRAF-mutated panNET could represent a subset characterized by an identifiable and clinically actionable driver. Following the identification of two patients w...

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Detalles Bibliográficos
Autores principales: Allen, Amy, Qin, Alice Can Ran, Raj, Nitya, Wang, Jiawan, Uddin, Sharmeen, Yao, Zhan, Tang, Laura, Meyers, Paul A., Taylor, Barry S., Berger, Michael F., Yaeger, Rona, Reidy-Lagunes, Diane, Pratilas, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546234/
https://www.ncbi.nlm.nih.gov/pubmed/31158244
http://dx.doi.org/10.1371/journal.pone.0217399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546234/
https://www.ncbi.nlm.nih.gov/pubmed/31158244
http://dx.doi.org/10.1371/journal.pone.0217399

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