The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ΔmucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection

Mucoid mucA22 Pseudomonas aeruginosa (PA) is an opportunistic lung pathogen of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients that is highly sensitive to acidified nitrite (A-NO(2)(-)). In this study, we first screened PA mutant strains for sensitivity or resistance t...

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Detalles Bibliográficos
Autores principales: Panmanee, Warunya, Su, Shengchang, Schurr, Michael J., Lau, Gee W., Zhu, Xiaoting, Ren, Zhaowei, McDaniel, Cameron T., Lu, Long J., Ohman, Dennis E., Muruve, Daniel A., Panos, Ralph J., Yu, Hongwei D., Thompson, Thomas B., Tseng, Boo Shan, Hassett, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546240/
https://www.ncbi.nlm.nih.gov/pubmed/31158231
http://dx.doi.org/10.1371/journal.pone.0216401

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