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DNA replication roadblocks caused by Cascade interference complexes are alleviated by RecG DNA repair helicase

Cascade complexes underpin E. coli CRISPR-Cas immunity systems by stimulating ‘adaptation’ reactions that update immunity and by initiating ‘interference’ reactions that destroy invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subsequent integration i...

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Detalles Bibliográficos
Autores principales: Killelea, Tom, Hawkins, Michelle, Howard, Jamieson L., McGlynn, Peter, Bolt, Edward L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546356/
https://www.ncbi.nlm.nih.gov/pubmed/30096986
http://dx.doi.org/10.1080/15476286.2018.1496773