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DNA replication roadblocks caused by Cascade interference complexes are alleviated by RecG DNA repair helicase
Cascade complexes underpin E. coli CRISPR-Cas immunity systems by stimulating ‘adaptation’ reactions that update immunity and by initiating ‘interference’ reactions that destroy invader DNA. Recognition of invader DNA in Cascade catalysed R-loops provokes DNA capture and its subsequent integration i...
Autores principales: | Killelea, Tom, Hawkins, Michelle, Howard, Jamieson L., McGlynn, Peter, Bolt, Edward L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546356/ https://www.ncbi.nlm.nih.gov/pubmed/30096986 http://dx.doi.org/10.1080/15476286.2018.1496773 |
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