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PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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Detalles Bibliográficos
Autores principales:	Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546366/ https://www.ncbi.nlm.nih.gov/pubmed/30109815 http://dx.doi.org/10.1080/15476286.2018.1504546

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