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Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems

Trans-activating CRISPR (tracr) RNA is a distinct RNA species that interacts with the CRISPR (cr) RNA to form the dual guide (g) RNA in type II and subtype V-B CRISPR-Cas systems. The tracrRNA-crRNA interaction is essential for pre-crRNA processing as well as target recognition and cleavage. The tra...

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Detalles Bibliográficos
Autores principales:	Faure, Guilhem, Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Crawley, Alexandra B., Barrangou, Rodolphe, Koonin, Eugene V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546382/ https://www.ncbi.nlm.nih.gov/pubmed/30103650 http://dx.doi.org/10.1080/15476286.2018.1493331

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