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Genome-lamina interactions are established de novo in the early mouse embryo
In mammals, the emergence of totipotency after fertilization involves extensive rearrangements of the spatial positioning of the genome1,2. However, the contribution of spatial genome organization to the regulation of developmental programs is unclear3. Here, we have generated high-resolution maps i...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546605/ https://www.ncbi.nlm.nih.gov/pubmed/31118510 http://dx.doi.org/10.1038/s41586-019-1233-0 |