Cargando…

Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes

Autophagy is active during cellular remodeling including muscle differentiation. Muscle differentiation is dysregulated in type 2 diabetes and we therefore hypothesize that muscle precursor cells from people with type 2 diabetes (T2DM) have a dysregulation of their autophagy leading to impaired myog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Henriksen, T. I., Wigge, L. V., Nielsen, J., Pedersen, B. K., Sandri, M., Scheele, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546785/ https://www.ncbi.nlm.nih.gov/pubmed/31160616 http://dx.doi.org/10.1038/s41598-019-44535-2

Ejemplares similares

Single Cell Analysis Identifies the miRNA Expression Profile of a Subpopulation of Muscle Precursor Cells Unique to Humans With Type 2 Diabetes
por: Henriksen, Tora I., et al.
Publicado: (2018)

Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes
por: Henriksen, Tora I., et al.
Publicado: (2017)

Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes
por: Väremo, Leif, et al.
Publicado: (2017)

Autophagy dysregulation in Danon disease
por: Nascimbeni, Anna Chiara, et al.
Publicado: (2017)

VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
por: Davegårdh, Cajsa, et al.
Publicado: (2021)

Endothelial Autophagy Dysregulation in Diabetes
por: Salemkour, Yann, et al.
Publicado: (2023)

Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
por: Davegårdh, Cajsa, et al.
Publicado: (2019)

Lifelong Physical Activity Prevents Aging-Associated Insulin Resistance in Human Skeletal Muscle Myotubes via Increased Glucose Transporter Expression
por: Bunprajun, Tipwadee, et al.
Publicado: (2013)

Satellite Cells Derived from Obese Humans with Type 2 Diabetes and Differentiated into Myocytes In Vitro Exhibit Abnormal Response to IL-6
por: Scheele, Camilla, et al.
Publicado: (2012)

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes
por: Pedersen, Helle Krogh, et al.
Publicado: (2017)

Elevated NF-κB Activation Is Conserved in Human Myocytes Cultured From Obese Type 2 Diabetic Patients and Attenuated by AMP-Activated Protein Kinase
por: Green, Charlotte J., et al.
Publicado: (2011)

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
por: Gallagher, Iain J, et al.
Publicado: (2010)

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome()()
por: Sandri, Marco
Publicado: (2013)

Plasma and Muscle Myostatin in Relation to Type 2 Diabetes
por: Brandt, Claus, et al.
Publicado: (2012)

Autophagy Dysregulation in Diabetic Kidney Disease: From Pathophysiology to Pharmacological Interventions
por: Gonzalez, Claudio D., et al.
Publicado: (2021)

Deficiency of mitochondrial aldehyde dehydrogenase increases type 2 diabetes risk in males via autophagy dysregulation
por: Liu, Xiang-Wei, et al.
Publicado: (2021)

Editorial: Autophagy and Mitophagy in Skeletal Muscle Health and Disease
por: Hussain, Sabah N. A., et al.
Publicado: (2021)

The critical role of dysregulated autophagy in the progression of diabetic kidney disease
por: Zhang, Ziwei, et al.
Publicado: (2022)

Autophagy and Skeletal Muscles in Sepsis
por: Mofarrahi, Mahroo, et al.
Publicado: (2012)

Dysregulation of autophagy in human follicular lymphoma is independent of overexpression of BCL-2
por: McCarthy, Aine, et al.
Publicado: (2014)

Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy
por: Marcelo, Adriana, et al.
Publicado: (2021)

Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes
por: Bork-Jensen, Jette, et al.
Publicado: (2014)

Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells
por: Jespersen, Naja Z., et al.
Publicado: (2019)

Culprits or consequences: Understanding the metabolic dysregulation of muscle in diabetes
por: O'Reilly, Colleen L, et al.
Publicado: (2021)

How Parkinsonian Toxins Dysregulate the Autophagy Machinery
por: Dagda, Ruben K., et al.
Publicado: (2013)

Dysregulation of Autophagy Contributes to Anal Carcinogenesis
por: Carchman, Evie H., et al.
Publicado: (2016)

Autophagy Dysregulation and Obesity-Associated Pathologies
por: Namkoong, Sim, et al.
Publicado: (2018)

Autophagy in Neurotrauma: Good, Bad, or Dysregulated
por: Wu, Junfang, et al.
Publicado: (2019)

Dysregulation of mTORC1/autophagy axis in senescence
por: Carroll, Bernadette, et al.
Publicado: (2017)

Diabetes-Induced Autophagy Dysregulation Engenders Testicular Impairment via Oxidative Stress
por: Xu, Renfeng, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress and Dysregulated Autophagy in Human Pancreatic Beta Cells
por: Moon, Seoil, et al.
Publicado: (2022)

An Overview of the Perspective of Cellular Autophagy: Mechanism, Regulation, and the Role of Autophagy Dysregulation in the Pathogenesis of Diseases
por: Alharbi, Yasser M., et al.
Publicado: (2021)

Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure
por: Fredriksson, Katarina, et al.
Publicado: (2008)

Alcohol-Induced Molecular Dysregulation in Human Embryonic Stem Cell-Derived Neural Precursor Cells
por: Kim, Yi Young, et al.
Publicado: (2016)

Neurovascular Dysregulation During Exercise in Type 2 Diabetes
por: Grotle, Ann-Katrin, et al.
Publicado: (2021)

Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
por: Ly, Luong Dai, et al.
Publicado: (2017)

Role of autophagy machinery dysregulation in bacterial chondronecrosis with osteomyelitis
por: Ramser, Alison, et al.
Publicado: (2022)

Correction: Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure
por: Fredriksson, Katarina, et al.
Publicado: (2008)

Diabetes diminishes muscle precursor cell-mediated microvascular angiogenesis
por: Acosta, Francisca M., et al.
Publicado: (2023)

Dysregulation of autophagy and mitochondrial function in Parkinson’s disease
por: Wang, Bao, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iv81e4l3cgje5k68f88udcm3j0