Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death

Therapy-induced presentation of cell surface calreticulin (CRT) is a pro-phagocytic immunogen beneficial for invoking anti-tumor immunity. Here, we characterized the roles of ERp57 and α-integrins as CRT-interacting proteins that coordinately regulate CRT translocation from the ER to the surface dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chi-Chao, Leclair, Pascal, Pedari, Foujan, Vieira, Heidi, Monajemi, Mahdis, Sly, Laura M., Reid, Gregor S., Lim, Chinten James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546883/
https://www.ncbi.nlm.nih.gov/pubmed/31192123
http://dx.doi.org/10.3389/fonc.2019.00411

Ejemplares similares

Ejemplares similares