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Rational Combination of Parvovirus H1 With CTLA-4 and PD-1 Checkpoint Inhibitors Dampens the Tumor Induced Immune Silencing

The recent therapeutic success of immune checkpoint inhibitors in the treatment of advanced melanoma highlights the potential of cancer immunotherapy. Oncolytic virus-based therapies may further improve the outcome of these cancer patients. A human ex vivo melanoma model was used to investigate the...

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Detalles Bibliográficos
Autores principales:	Goepfert, Katrin, Dinsart, Christiane, Rommelaere, Jean, Foerster, Friedrich, Moehler, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546938/ https://www.ncbi.nlm.nih.gov/pubmed/31192129 http://dx.doi.org/10.3389/fonc.2019.00425

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