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Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study

IMPORTANCE: Positron emission tomography (PET) imaging now allows in vivo visualization of both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau neurofibrillary tangles. Observing their progressive accumulation in the brains of clinically normal older adults is cri...

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Detalles Bibliográficos
Autores principales: Hanseeuw, Bernard J., Betensky, Rebecca A., Jacobs, Heidi I. L., Schultz, Aaron P., Sepulcre, Jorge, Becker, J. Alex, Cosio, Danielle M. Orozco, Farrell, Michelle, Quiroz, Yakeel T., Mormino, Elizabeth C., Buckley, Rachel F., Papp, Kathryn V., Amariglio, Rebecca A., Dewachter, Ilse, Ivanoiu, Adrian, Huijbers, Willem, Hedden, Trey, Marshall, Gad A., Chhatwal, Jasmeer P., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547132/
https://www.ncbi.nlm.nih.gov/pubmed/31157827
http://dx.doi.org/10.1001/jamaneurol.2019.1424