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Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study
IMPORTANCE: Positron emission tomography (PET) imaging now allows in vivo visualization of both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau neurofibrillary tangles. Observing their progressive accumulation in the brains of clinically normal older adults is cri...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547132/ https://www.ncbi.nlm.nih.gov/pubmed/31157827 http://dx.doi.org/10.1001/jamaneurol.2019.1424 |