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Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study
IMPORTANCE: Positron emission tomography (PET) imaging now allows in vivo visualization of both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau neurofibrillary tangles. Observing their progressive accumulation in the brains of clinically normal older adults is cri...
Autores principales: | Hanseeuw, Bernard J., Betensky, Rebecca A., Jacobs, Heidi I. L., Schultz, Aaron P., Sepulcre, Jorge, Becker, J. Alex, Cosio, Danielle M. Orozco, Farrell, Michelle, Quiroz, Yakeel T., Mormino, Elizabeth C., Buckley, Rachel F., Papp, Kathryn V., Amariglio, Rebecca A., Dewachter, Ilse, Ivanoiu, Adrian, Huijbers, Willem, Hedden, Trey, Marshall, Gad A., Chhatwal, Jasmeer P., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547132/ https://www.ncbi.nlm.nih.gov/pubmed/31157827 http://dx.doi.org/10.1001/jamaneurol.2019.1424 |
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