Etiology of Adolescent Idiopathic Scoliosis: A Literature Review

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine bot...

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Detalles Bibliográficos
Autores principales: Kikanloo, Sina Rashidi, Tarpada, Sandip Parshottam, Cho, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Spine Surgery 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547389/
https://www.ncbi.nlm.nih.gov/pubmed/30744305
http://dx.doi.org/10.31616/asj.2018.0096
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author Kikanloo, Sina Rashidi
Tarpada, Sandip Parshottam
Cho, Woojin
author_facet Kikanloo, Sina Rashidi
Tarpada, Sandip Parshottam
Cho, Woojin
author_sort Kikanloo, Sina Rashidi
collection PubMed
description Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.
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spelling pubmed-65473892019-06-17 Etiology of Adolescent Idiopathic Scoliosis: A Literature Review Kikanloo, Sina Rashidi Tarpada, Sandip Parshottam Cho, Woojin Asian Spine J Review Article Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS. Korean Society of Spine Surgery 2019-06 2019-02-13 /pmc/articles/PMC6547389/ /pubmed/30744305 http://dx.doi.org/10.31616/asj.2018.0096 Text en Copyright © 2019 by Korean Society of Spine Surgery This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kikanloo, Sina Rashidi
Tarpada, Sandip Parshottam
Cho, Woojin
Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_full Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_fullStr Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_full_unstemmed Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_short Etiology of Adolescent Idiopathic Scoliosis: A Literature Review
title_sort etiology of adolescent idiopathic scoliosis: a literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547389/
https://www.ncbi.nlm.nih.gov/pubmed/30744305
http://dx.doi.org/10.31616/asj.2018.0096
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