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Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion
STUDY DESIGN: Experimental human study. PURPOSE: To determine whether angiopoietin-like protein 2 (ANGPTL2) is highly expressed in the hyperplastic facet joint (FJ) synovium and whether it activates interleukin-6 (IL-6) secretion in FJ synoviocytes. OVERVIEW OF LITERATURE: Mechanical stress-induced...
Autores principales: | Sugimoto, Kazuki, Nakamura, Takayuki, Tokunaga, Takuya, Uehara, Yusuke, Okada, Tatsuya, Taniwaki, Takuya, Fujimoto, Toru, Oike, Yuichi, Nakamura, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Spine Surgery
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547404/ https://www.ncbi.nlm.nih.gov/pubmed/30685956 http://dx.doi.org/10.31616/asj.2018.0178 |
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