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Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion

STUDY DESIGN: Experimental human study. PURPOSE: To determine whether angiopoietin-like protein 2 (ANGPTL2) is highly expressed in the hyperplastic facet joint (FJ) synovium and whether it activates interleukin-6 (IL-6) secretion in FJ synoviocytes. OVERVIEW OF LITERATURE: Mechanical stress-induced...

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Detalles Bibliográficos
Autores principales: Sugimoto, Kazuki, Nakamura, Takayuki, Tokunaga, Takuya, Uehara, Yusuke, Okada, Tatsuya, Taniwaki, Takuya, Fujimoto, Toru, Oike, Yuichi, Nakamura, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Spine Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547404/
https://www.ncbi.nlm.nih.gov/pubmed/30685956
http://dx.doi.org/10.31616/asj.2018.0178

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