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A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication

Replication of sufficient mitochondrial DNA (mtDNA) is essential for maintaining mitochondrial functions in mammalian cells. During mtDNA replication, RNA primers must be removed before the nascent circular DNA strands rejoin. This process involves mitochondrial RNase H1, which removes most of the R...

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Detalles Bibliográficos
Autores principales:	Wu, Chyuan-Chuan, Lin, Jason L J, Yang-Yen, Hsin-Fang, Yuan, Hanna S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547421/ https://www.ncbi.nlm.nih.gov/pubmed/30949702 http://dx.doi.org/10.1093/nar/gkz241

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