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Direct removal of RNA polymerase barriers to replication by accessory replicative helicases
Bacterial genome duplication and transcription require simultaneous access to the same DNA template. Conflicts between the replisome and transcription machinery can lead to interruption of DNA replication and loss of genome stability. Pausing, stalling and backtracking of transcribing RNA polymerase...
Autores principales: | Hawkins, Michelle, Dimude, Juachi U, Howard, Jamieson A L, Smith, Abigail J, Dillingham, Mark S, Savery, Nigel J, Rudolph, Christian J, McGlynn, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547429/ https://www.ncbi.nlm.nih.gov/pubmed/30869136 http://dx.doi.org/10.1093/nar/gkz170 |
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