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Cycloheximide can distort measurements of mRNA levels and translation efficiency

Regulation of the efficiency with which an mRNA is translated into proteins represents a key mechanism for controlling gene expression. Such regulation impacts the number of actively translating ribosomes per mRNA molecule, referred to as translation efficiency (TE), which can be monitored using rib...

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Detalles Bibliográficos
Autores principales:	Santos, Daniel A, Shi, Lei, Tu, Benjamin P, Weissman, Jonathan S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Data Resources and Analyses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547433/ https://www.ncbi.nlm.nih.gov/pubmed/30916348 http://dx.doi.org/10.1093/nar/gkz205

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