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Replication dynamics of individual loci in single living cells reveal changes in the degree of replication stochasticity through S phase

Eukaryotic genomes are replicated under the control of a highly sophisticated program during the restricted time period corresponding to S phase. The most widely used replication timing assays, which are performed on populations of millions of cells, suggest that most of the genome is synchronously...

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Detalles Bibliográficos
Autores principales: Duriez, Bénédicte, Chilaka, Sabarinadh, Bercher, Jean-François, Hercul, Eslande, Prioleau, Marie-Noëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547449/
https://www.ncbi.nlm.nih.gov/pubmed/30926993
http://dx.doi.org/10.1093/nar/gkz220