Sources of artifact in measurements of 6mA and 4mC abundance in eukaryotic genomic DNA

BACKGROUND: Directed DNA methylation on N6-adenine (6mA), N4-cytosine (4mC), and C5-cytosine (5mC) can potentially increase DNA coding capacity and regulate a variety of biological functions. These modifications are relatively abundant in bacteria, occurring in about a percent of all bases of most b...

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Detalles Bibliográficos
Autores principales: O’Brown, Zach K., Boulias, Konstantinos, Wang, Jie, Wang, Simon Yuan, O’Brown, Natasha M., Hao, Ziyang, Shibuya, Hiroki, Fady, Paul-Enguerrand, Shi, Yang, He, Chuan, Megason, Sean G., Liu, Tao, Greer, Eric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547475/
https://www.ncbi.nlm.nih.gov/pubmed/31159718
http://dx.doi.org/10.1186/s12864-019-5754-6

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