Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks

BACKGROUND: Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a novel strategy to integrate gene expression profiles across 32 cancer types, and c...

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Detalles Bibliográficos
Autores principales: Walters, Kevin, Sarsenov, Radmir, Too, Wen Siong, Hare, Roseanna K., Paterson, Ian C., Lambert, Daniel W., Brown, Stephen, Bradford, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547491/
https://www.ncbi.nlm.nih.gov/pubmed/31159744
http://dx.doi.org/10.1186/s12864-019-5850-7

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