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New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools
BACKGROUND: Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and a high rate of recurrence. Primary and acquired platinum resistance is related to a low response probability to subsequent lines of treatment and to a poor survival. Therefore, a...
Autores principales: | Muñoz-Galván, Sandra, Felipe-Abrio, Blanca, García-Carrasco, Miguel, Domínguez-Piñol, Julia, Suarez-Martinez, Elisa, Verdugo-Sivianes, Eva M., Espinosa-Sánchez, Asunción, Navas, Lola E., Otero-Albiol, Daniel, Marin, Juan J., Jiménez-García, Manuel P., García-Heredia, Jose M., Quiroga, Adoración G., Estevez-Garcia, Purificacion, Carnero, Amancio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547556/ https://www.ncbi.nlm.nih.gov/pubmed/31159852 http://dx.doi.org/10.1186/s13046-019-1245-5 |
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