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Inositol pyrophosphates mediated the apoptosis induced by hypoxic injury in bone marrow-derived mesenchymal stem cells by autophagy
OBJECTIVE: To investigate the potential effect of IP7 on the autophagy and apoptosis of bone marrow mesenchymal stem cells (BM-MSCs) caused by hypoxia. METHODS: BM-MSCs isolated from adult male C57BL/6 mice were exposed to normoxic condition and hypoxic stress for 6 h, 12 h, and 24 h, respectively....
Autores principales: | Deng, Jingyu, Yang, Chao, Wang, Yong, Yang, Ming, Chen, Haixu, Ning, Hongjuan, Wang, Chengzhu, Liu, Yanjun, Zhang, Zheng, Hu, Taohong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547565/ https://www.ncbi.nlm.nih.gov/pubmed/31159888 http://dx.doi.org/10.1186/s13287-019-1256-3 |
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