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Chromatin accessibility plays a key role in selective targeting of Hox proteins

BACKGROUND: Hox transcription factors specify segmental diversity along the anterior-posterior body axis in metazoans. While the different Hox family members show clear functional specificity in vivo, they all show similar binding specificity in vitro and a satisfactory understanding of in vivo Hox...

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Detalles Bibliográficos
Autores principales: Porcelli, Damiano, Fischer, Bettina, Russell, Steven, White, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547607/
https://www.ncbi.nlm.nih.gov/pubmed/31159833
http://dx.doi.org/10.1186/s13059-019-1721-4