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Mapping the allosteric network within a SH3 domain

SH3 domains are very abundant protein-protein interactions modules, involved in the regulation of several cellular processes. Whilst they have been associated to allosteric communication pathways between contiguous domains in multi-domain proteins, there is lack of information regarding the intra-do...

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Detalles Bibliográficos
Autores principales: Malagrinò, Francesca, Troilo, Francesca, Bonetti, Daniela, Toto, Angelo, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547694/
https://www.ncbi.nlm.nih.gov/pubmed/31164678
http://dx.doi.org/10.1038/s41598-019-44656-8