Activation of Aurora A kinase increases YAP stability via blockage of autophagy

Transcription cofactor Yes-associated protein (YAP) plays an important role in cancer progression. Here, we found that Aurora A kinase expression was positively correlated with YAP in lung cancer. Aurora A depletion suppresses lung cancer cell colony formation, which could be reversed by YAP ectopic...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Gong, Ying, Guo, Tao, Li, Man, Fang, Lei, Yin, Shengchen, Kamran, Muhammad, Liu, Yang, Xu, Jie, Xu, Lingzhi, Peng, Fei, Xue, Xiaoyuan, Yang, Mengying, Hung, Mie-Chie, Lam, Eric W.-F., Gu, Chundong, Wang, Chunli, Zhan, Qimin, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547697/
https://www.ncbi.nlm.nih.gov/pubmed/31160567
http://dx.doi.org/10.1038/s41419-019-1664-4

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