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Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation

Enhancer of zeste homolog 2 (EZH2)-mediated trimethylation of histone 3 lysine 27 (H3K27Me3) is critical for immune regulation. However, evidence is lacking to address the effect of EZH2 enzyme’s activity on intestinal immune responses during inflammatory bowel disease (IBD). Here we report that sup...

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Detalles Bibliográficos
Autores principales:	Zhou, Jie, Huang, Shuo, Wang, Zhongyu, Huang, Jiani, Xu, Liang, Tang, Xuefeng, Wan, Yisong Y., Li, Qi-jing, Symonds, Alistair L. J., Long, Haixia, Zhu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547712/ https://www.ncbi.nlm.nih.gov/pubmed/31160593 http://dx.doi.org/10.1038/s41467-019-10176-2

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