CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

Tumor-associated myeloid cells regulate tumor growth and metastasis, and their accumulation is a negative prognostic factor for breast cancer. Here we find calcium/calmodulin-dependent kinase kinase (CaMKK2) to be highly expressed within intratumoral myeloid cells in mouse models of breast cancer, a...

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Detalles Bibliográficos
Autores principales: Racioppi, Luigi, Nelson, Erik R., Huang, Wei, Mukherjee, Debarati, Lawrence, Scott A., Lento, William, Masci, Anna Maria, Jiao, Yiquin, Park, Sunghee, York, Brian, Liu, Yaping, Baek, Amy E., Drewry, David H., Zuercher, William J., Bertani, Francesca R., Businaro, Luca, Geradts, Joseph, Hall, Allison, Means, Anthony R., Chao, Nelson, Chang, Ching-yi, McDonnell, Donald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547743/
https://www.ncbi.nlm.nih.gov/pubmed/31164648
http://dx.doi.org/10.1038/s41467-019-10424-5

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