Antagonism between BRCA2 and FIGL1 regulates homologous recombination

Homologous recombination (HR) maintains genome stability by promoting accurate DNA repair. Two recombinases, RAD51 and DMC1, are central to HR repair and form dynamic nucleoprotein filaments in vivo under tight regulation. However, the interplay between positive and negative regulators to control th...

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Detalles Bibliográficos
Autores principales: Kumar, Rajeev, Duhamel, Marine, Coutant, Eve, Ben-Nahia, Emna, Mercier, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547764/
https://www.ncbi.nlm.nih.gov/pubmed/30941419
http://dx.doi.org/10.1093/nar/gkz225

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