IL2RB maintains immune harmony

How the IL-2 receptor β-chain specifically shapes immunity has remained enigmatic. In this issue of JEM, Zhang et al. (https://doi.org/10.1084/jem.20182304) and Fernandez et al. (https://doi.org/10.1084/jem.20182015) independently report the first observations of autosomal recessive mutations in IL2...

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Detalles Bibliográficos
Autores principales: Campbell, Tessa M., Bryceson, Yenan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547856/
https://www.ncbi.nlm.nih.gov/pubmed/31068380
http://dx.doi.org/10.1084/jem.20190546
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author Campbell, Tessa M.
Bryceson, Yenan T.
author_facet Campbell, Tessa M.
Bryceson, Yenan T.
author_sort Campbell, Tessa M.
collection PubMed
description How the IL-2 receptor β-chain specifically shapes immunity has remained enigmatic. In this issue of JEM, Zhang et al. (https://doi.org/10.1084/jem.20182304) and Fernandez et al. (https://doi.org/10.1084/jem.20182015) independently report the first observations of autosomal recessive mutations in IL2RB, revealing a requirement for IL2RB in immunity and peripheral immune tolerance.
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spelling pubmed-65478562019-12-04 IL2RB maintains immune harmony Campbell, Tessa M. Bryceson, Yenan T. J Exp Med News How the IL-2 receptor β-chain specifically shapes immunity has remained enigmatic. In this issue of JEM, Zhang et al. (https://doi.org/10.1084/jem.20182304) and Fernandez et al. (https://doi.org/10.1084/jem.20182015) independently report the first observations of autosomal recessive mutations in IL2RB, revealing a requirement for IL2RB in immunity and peripheral immune tolerance. Rockefeller University Press 2019-06-03 2019-05-08 /pmc/articles/PMC6547856/ /pubmed/31068380 http://dx.doi.org/10.1084/jem.20190546 Text en © 2019 Campbell and Bryceson http://www.rupress.org/terms/http://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Campbell, Tessa M.
Bryceson, Yenan T.
IL2RB maintains immune harmony
title IL2RB maintains immune harmony
title_full IL2RB maintains immune harmony
title_fullStr IL2RB maintains immune harmony
title_full_unstemmed IL2RB maintains immune harmony
title_short IL2RB maintains immune harmony
title_sort il2rb maintains immune harmony
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547856/
https://www.ncbi.nlm.nih.gov/pubmed/31068380
http://dx.doi.org/10.1084/jem.20190546
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