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Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response
Regnase-1 (also known as Zc3h12a or MCPIP-1) is an endoribonuclease involved in mRNA degradation of inflammation-associated genes. Regnase-1 is inactivated in response to external stimuli through post-translational modifications including phosphorylation, yet the precise role of phosphorylation rema...
Autores principales: | Tanaka, Hiroki, Arima, Yasunobu, Kamimura, Daisuke, Tanaka, Yuki, Takahashi, Noriyuki, Uehata, Takuya, Maeda, Kazuhiko, Satoh, Takashi, Murakami, Masaaki, Akira, Shizuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547859/ https://www.ncbi.nlm.nih.gov/pubmed/31072819 http://dx.doi.org/10.1084/jem.20181078 |
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