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HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells
A small number of HIV-1–infected individuals develop broadly neutralizing antibodies to the virus (bNAbs). These antibodies are protective against infection in animal models. However, they only emerge 1–3 yr after infection, and show a number of highly unusual features including exceedingly high lev...
Autores principales: | Hartweger, Harald, McGuire, Andrew T., Horning, Marcel, Taylor, Justin J., Dosenovic, Pia, Yost, Daniel, Gazumyan, Anna, Seaman, Michael S., Stamatatos, Leonidas, Jankovic, Mila, Nussenzweig, Michel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547862/ https://www.ncbi.nlm.nih.gov/pubmed/30975893 http://dx.doi.org/10.1084/jem.20190287 |
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