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Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity
Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages in mice promotes bacterial clearance in the per...
Autores principales: | Zhang, Nan, Czepielewski, Rafael S., Jarjour, Nicholas N., Erlich, Emma C., Esaulova, Ekaterina, Saunders, Brian T., Grover, Steven P., Cleuren, Audrey C., Broze, George J., Edelson, Brian T., Mackman, Nigel, Zinselmeyer, Bernd H., Randolph, Gwendalyn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547866/ https://www.ncbi.nlm.nih.gov/pubmed/31048328 http://dx.doi.org/10.1084/jem.20182024 |
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