Cargando…

Inactivation of farR Causes High Rhodomyrtone Resistance and Increased Pathogenicity in Staphylococcus aureus

Rhodomyrtone (Rom) is an acylphloroglucinol antibiotic originally isolated from leaves of Rhodomyrtus tomentosa. Rom targets the bacterial membrane and is active against a wide range of Gram-positive bacteria but the exact mode of action remains obscure. Here we isolated and characterized a spontane...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Minh-Thu, Saising, Jongkon, Tribelli, Paula Maria, Nega, Mulugeta, Diene, Seydina M., François, Patrice, Schrenzel, Jacques, Spröer, Cathrin, Bunk, Boyke, Ebner, Patrick, Hertlein, Tobias, Kumari, Nimerta, Härtner, Thomas, Wistuba, Dorothee, Voravuthikunchai, Supayang P., Mäder, Ulrike, Ohlsen, Knut, Götz, Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547885/ https://www.ncbi.nlm.nih.gov/pubmed/31191485 http://dx.doi.org/10.3389/fmicb.2019.01157

Ejemplares similares

Liposomal Encapsulated Rhodomyrtone: A Novel Antiacne Drug
por: Chorachoo, Julalak, et al.
Publicado: (2013)

Ethnomedicinal Plants in Herbal Remedies Used for Treatment of Skin Diseases by Traditional Healers in Songkhla Province, Thailand
por: Saising, Jongkon, et al.
Publicado: (2022)

Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus
por: Reichert, Sebastian, et al.
Publicado: (2018)

Genomic and Transcriptional Profiling Analysis and Insights into Rhodomyrtone Yield in Rhodomyrtus tomentosa (Aiton) Hassk
por: Nakkaew, Alisa, et al.
Publicado: (2023)

Transcriptome Analysis of Responses to Rhodomyrtone in Methicillin-Resistant Staphylococcus aureus
por: Sianglum, Wipawadee, et al.
Publicado: (2012)

Antibacterial mechanism of rhodomyrtone involves the disruption of nucleoid segregation checkpoint in Streptococcus suis
por: Traithan, Apichaya, et al.
Publicado: (2020)

Correction: Transcriptome Analysis of Responses to Rhodomyrtone in Methicillin-Resistant Staphylococcus aureus
por: Sianglum, Wipawadee, et al.
Publicado: (2013)

Effects of rhodomyrtone on Gram-positive bacterial tubulin homologue FtsZ
por: Saeloh, Dennapa, et al.
Publicado: (2017)

Rhodomyrtone Modulates Innate Immune Responses of THP-1 Monocytes to Assist in Clearing Methicillin-Resistant Staphylococcus aureus
por: Srisuwan, Sutthirat, et al.
Publicado: (2014)

The novel antibiotic rhodomyrtone traps membrane proteins in vesicles with increased fluidity
por: Saeloh, Dennapa, et al.
Publicado: (2018)

Proteome Analyses of Cellular Proteins in Methicillin-Resistant Staphylococcus aureus Treated with Rhodomyrtone, a Novel Antibiotic Candidate
por: Sianglum, Wipawadee, et al.
Publicado: (2011)

Rhodomyrtone Accumulates in Bacterial Cell Wall and Cell Membrane and Inhibits the Synthesis of Multiple Cellular Macromolecules in Epidemic Methicillin-Resistant Staphylococcus aureus
por: Nwabor, Ozioma F., et al.
Publicado: (2021)

In vivo safety assessment of rhodomyrtone, a potent compound, from Rhodomyrtus tomentosa leaf extract
por: Siriyong, Thanyaluck, et al.
Publicado: (2020)

Integrated proteomic and metabolomic analysis reveals that rhodomyrtone reduces the capsule in Streptococcus pneumoniae
por: Mitsuwan, Watcharapong, et al.
Publicado: (2017)

Rhodomyrtone as a New Natural Antibiotic Isolated from Rhodomyrtus tomentosa Leaf Extract: A Clinical Application in the Management of Acne Vulgaris
por: Wunnoo, Suttiwan, et al.
Publicado: (2021)

The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasis
por: Chorachoo, Julalak, et al.
Publicado: (2018)

Complete Genome Sequence of Mycobacterium avium subsp. avium Chester (DSM 44156)
por: Goethe, Ralph, et al.
Publicado: (2020)

Dr Farr
Publicado: (1880)

Complete Genome Sequence of Highly Adherent Pseudomonas aeruginosa Small-Colony Variant SCV20265
por: Eckweiler, Denitsa, et al.
Publicado: (2014)

Complete Genome Sequence of the Silicimonas algicola Type Strain, a Representative of the Marine Roseobacter Group Isolated from the Cell Surface of the Marine Diatom Thalassiosira delicatula
por: Crenn, Klervi, et al.
Publicado: (2019)

Complete Genome Sequences of Two Novel Species from the Pseudonocardiaceae Family Isolated from the Persian Gulf
por: Safaei, Nasim, et al.
Publicado: (2021)

Frederick George Farr
Publicado: (1924)

Molecular Basis of Rhodomyrtone Resistance in Staphylococcus aureus
por: Huang, Li, et al.
Publicado: (2022)

Complete Genome Sequence of Nocardia iowensis DSM 45197(T) (= NRRL 5646(T))
por: Collins Fairclough, Aneisha, et al.
Publicado: (2023)

OxyR-dependent formation of DNA methylation patterns in OpvAB(OFF) and OpvAB(ON) cell lineages of Salmonella enterica
por: Cota, Ignacio, et al.
Publicado: (2016)

Complete Genome Sequence of the Novel Temperate Clostridium difficile Phage phiCDIF1296T
por: Wittmann, Johannes, et al.
Publicado: (2015)

First Complete Genome Sequence of a Subdivision 6 Acidobacterium Strain
por: Huang, Sixing, et al.
Publicado: (2016)

Complete Genome Sequence of Raoultella electrica 1GB (DSM 102253(T)), Isolated from Anodic Biofilms of a Glucose-Fed Microbial Fuel Cell
por: Thiel, Simone, et al.
Publicado: (2019)

Thermococcus bergensis sp. nov., a Novel Hyperthermophilic Starch-Degrading Archaeon
por: Birkeland, Nils-Kåre, et al.
Publicado: (2021)

Portrait of J. R. Farre
Publicado: (1939)

Genome Sequence of Prosthecochloris sp. Strain CIB 2401 of the Phylum Chlorobi
por: Nabhan, Shaza, et al.
Publicado: (2016)

New insights in the coordinated amidase and glucosaminidase activity of the major autolysin (Atl) in Staphylococcus aureus
por: Nega, Mulugeta, et al.
Publicado: (2020)

Medical Statistics from Graunt to Farr
por: Herman, Samuel
Publicado: (1948)

Dr. Farre's Remonstrance to Mr. Stevenson
por: Farre, John Richard
Publicado: (1812)

Mr. Stevenson's Reply to Dr. Farre
por: Stevenson, John
Publicado: (1813)

Dr. Farre, on the Morbid Anatomy of the Liver
Publicado: (1816)

Reply to X. Farré et al
por: Vickers, Andrew, et al.
Publicado: (2023)

Complete Genome Sequence of the Urethral Catheter Isolate Myroides sp. A21
por: Burghartz, Melanie, et al.
Publicado: (2015)

Complete Genome Sequence of Kyrpidia sp. Strain EA-1, a Thermophilic Knallgas Bacterium, Isolated from the Azores
por: Reiner, Johannes Eberhard, et al.
Publicado: (2018)

Comparative Genomics Suggests Mechanisms of Genetic Adaptation toward the Catabolism of the Phenylurea Herbicide Linuron in Variovorax
por: Öztürk, Başak, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_35ardl8q42uvv2gsta12s56rac