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Hypertonic Saline in the Treatment of Hemorrhagic Shock
CONTEXT: The present review discusses different studies about the treatment of hemorrhagic shock (HS) with hypertonic saline (HTS). EVIDENCE ACQUISITION: We have searched the title in the most popular databases containing recent meta-analysis or randomized clinical trials (RCTs). RESULTS: We introdu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548092/ https://www.ncbi.nlm.nih.gov/pubmed/31172060 http://dx.doi.org/10.22114/AJEM.v1i1.2 |
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author | Vahidi, Elnaz Naderpour, Zeinab Saeedi, Morteza |
author_facet | Vahidi, Elnaz Naderpour, Zeinab Saeedi, Morteza |
author_sort | Vahidi, Elnaz |
collection | PubMed |
description | CONTEXT: The present review discusses different studies about the treatment of hemorrhagic shock (HS) with hypertonic saline (HTS). EVIDENCE ACQUISITION: We have searched the title in the most popular databases containing recent meta-analysis or randomized clinical trials (RCTs). RESULTS: We introduce the hemodynamic effects and mechanisms of action of HTS in HS. Evidence in this field shows controversial results. There are some data supporting the potential benefits of HTS infusion in HS. The goal of research in this field is to identify the best therapy in HS with the least mortality. CONCLUSION: Our conclusion shows that although HTS can decrease inflammatory response during HS, it can attenuate hypercoagulability and cause complications. There are no data supporting less mortality while treatment with HTS versus other fluids in HS. |
format | Online Article Text |
id | pubmed-6548092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-65480922019-06-06 Hypertonic Saline in the Treatment of Hemorrhagic Shock Vahidi, Elnaz Naderpour, Zeinab Saeedi, Morteza Adv J Emerg Med Review Article CONTEXT: The present review discusses different studies about the treatment of hemorrhagic shock (HS) with hypertonic saline (HTS). EVIDENCE ACQUISITION: We have searched the title in the most popular databases containing recent meta-analysis or randomized clinical trials (RCTs). RESULTS: We introduce the hemodynamic effects and mechanisms of action of HTS in HS. Evidence in this field shows controversial results. There are some data supporting the potential benefits of HTS infusion in HS. The goal of research in this field is to identify the best therapy in HS with the least mortality. CONCLUSION: Our conclusion shows that although HTS can decrease inflammatory response during HS, it can attenuate hypercoagulability and cause complications. There are no data supporting less mortality while treatment with HTS versus other fluids in HS. Tehran University of Medical Sciences 2017-10-13 /pmc/articles/PMC6548092/ /pubmed/31172060 http://dx.doi.org/10.22114/AJEM.v1i1.2 Text en © 2017 Tehran University of Medical Sciences This open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 License (CC BY-NC 4.0). (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Review Article Vahidi, Elnaz Naderpour, Zeinab Saeedi, Morteza Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title | Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title_full | Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title_fullStr | Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title_full_unstemmed | Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title_short | Hypertonic Saline in the Treatment of Hemorrhagic Shock |
title_sort | hypertonic saline in the treatment of hemorrhagic shock |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548092/ https://www.ncbi.nlm.nih.gov/pubmed/31172060 http://dx.doi.org/10.22114/AJEM.v1i1.2 |
work_keys_str_mv | AT vahidielnaz hypertonicsalineinthetreatmentofhemorrhagicshock AT naderpourzeinab hypertonicsalineinthetreatmentofhemorrhagicshock AT saeedimorteza hypertonicsalineinthetreatmentofhemorrhagicshock |