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Bayonets over bombs: RIPK3 and MLKL restrict Listeria without triggering necroptosis

RIPK3 induces necroptosis by phosphorylating MLKL, which then induces plasma membrane rupture and necrotic cell death. In this issue, Sai et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201810014) show that RIPK3-MLKL signaling in epithelial cells promotes Listeria clearance by directly supp...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Balachandran, Siddharth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Commentaries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548124/ https://www.ncbi.nlm.nih.gov/pubmed/31097456 http://dx.doi.org/10.1083/jcb.201905047

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