Mutant p53 amplifies a dynamin-1/APPL1 endosome feedback loop that regulates recycling and migration

Multiple mechanisms contribute to cancer cell progression and metastatic activity, including changes in endocytic trafficking and signaling of cell surface receptors downstream of gain-of-function (GOF) mutant p53. We report that dynamin-1 (Dyn1) is up-regulated at both the mRNA and protein levels i...

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Detalles Bibliográficos
Autores principales: Lakoduk, Ashley M., Roudot, Philippe, Mettlen, Marcel, Grossman, Heather M., Schmid, Sandra L., Chen, Ping-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548126/
https://www.ncbi.nlm.nih.gov/pubmed/31043431
http://dx.doi.org/10.1083/jcb.201810183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548126/
https://www.ncbi.nlm.nih.gov/pubmed/31043431
http://dx.doi.org/10.1083/jcb.201810183

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