Rab5-dependent autophagosome closure by ESCRT

In the conserved autophagy pathway, autophagosomes (APs) engulf cellular components and deliver them to the lysosome for degradation. Before fusing with the lysosome, APs have to close via an unknown mechanism. We have previously shown that the endocytic Rab5-GTPase regulates AP closure. Therefore,...

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Detalles Bibliográficos
Autores principales: Zhou, Fan, Wu, Zulin, Zhao, Mengzhu, Murtazina, Rakhilya, Cai, Juan, Zhang, Ao, Li, Rui, Sun, Dan, Li, Wenjing, Zhao, Lei, Li, Qunli, Zhu, Jing, Cong, Xiaoxia, Zhou, Yiting, Xie, Zhiping, Gyurkovska, Valeriya, Li, Liuju, Huang, Xiaoshuai, Xue, Yanhong, Chen, Liangyi, Xu, Hui, Xu, Haiqian, Liang, Yongheng, Segev, Nava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548130/
https://www.ncbi.nlm.nih.gov/pubmed/31010855
http://dx.doi.org/10.1083/jcb.201811173

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