HDAC6 and Miro1: Another interaction causing trouble in neurons

Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extracellular matrix can prevent regeneration of injured axons. In this issue, Kalinski et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201702187) report that inhibition of HDAC6 prevents the deacetylation of Miro1,...

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Detalles Bibliográficos
Autor principal: Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548136/
https://www.ncbi.nlm.nih.gov/pubmed/31118238
http://dx.doi.org/10.1083/jcb.201904016
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author Van Den Bosch, Ludo
author_facet Van Den Bosch, Ludo
author_sort Van Den Bosch, Ludo
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description Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extracellular matrix can prevent regeneration of injured axons. In this issue, Kalinski et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201702187) report that inhibition of HDAC6 prevents the deacetylation of Miro1, increases mitochondrial axonal transport, and restores the size of axonal growth cones.
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spelling pubmed-65481362019-12-28 HDAC6 and Miro1: Another interaction causing trouble in neurons Van Den Bosch, Ludo J Cell Biol Commentaries Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extracellular matrix can prevent regeneration of injured axons. In this issue, Kalinski et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201702187) report that inhibition of HDAC6 prevents the deacetylation of Miro1, increases mitochondrial axonal transport, and restores the size of axonal growth cones. Rockefeller University Press 2019-06-28 2019-05-22 /pmc/articles/PMC6548136/ /pubmed/31118238 http://dx.doi.org/10.1083/jcb.201904016 Text en © 2019 Van Den Bosch http://www.rupress.org/terms/http://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Van Den Bosch, Ludo
HDAC6 and Miro1: Another interaction causing trouble in neurons
title HDAC6 and Miro1: Another interaction causing trouble in neurons
title_full HDAC6 and Miro1: Another interaction causing trouble in neurons
title_fullStr HDAC6 and Miro1: Another interaction causing trouble in neurons
title_full_unstemmed HDAC6 and Miro1: Another interaction causing trouble in neurons
title_short HDAC6 and Miro1: Another interaction causing trouble in neurons
title_sort hdac6 and miro1: another interaction causing trouble in neurons
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548136/
https://www.ncbi.nlm.nih.gov/pubmed/31118238
http://dx.doi.org/10.1083/jcb.201904016
work_keys_str_mv AT vandenboschludo hdac6andmiro1anotherinteractioncausingtroubleinneurons

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