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Somatic autophagy of axonal mitochondria in ischemic neurons

Mitophagy protects against ischemic neuronal injury by eliminating damaged mitochondria, but it is unclear how mitochondria in distal axons are cleared. We find that oxygen and glucose deprivation-reperfusion reduces mitochondrial content in both cell bodies and axons. Axonal mitochondria eliminatio...

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Detalles Bibliográficos
Autores principales: Zheng, Yanrong, Zhang, Xiangnan, Wu, Xiaoli, Jiang, Lei, Ahsan, Anil, Ma, Shijia, Xiao, Ziyu, Han, Feng, Qin, Zheng-Hong, Hu, Weiwei, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548140/
https://www.ncbi.nlm.nih.gov/pubmed/30979799
http://dx.doi.org/10.1083/jcb.201804101

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