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Somatic autophagy of axonal mitochondria in ischemic neurons
Mitophagy protects against ischemic neuronal injury by eliminating damaged mitochondria, but it is unclear how mitochondria in distal axons are cleared. We find that oxygen and glucose deprivation-reperfusion reduces mitochondrial content in both cell bodies and axons. Axonal mitochondria eliminatio...
Autores principales: | Zheng, Yanrong, Zhang, Xiangnan, Wu, Xiaoli, Jiang, Lei, Ahsan, Anil, Ma, Shijia, Xiao, Ziyu, Han, Feng, Qin, Zheng-Hong, Hu, Weiwei, Chen, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548140/ https://www.ncbi.nlm.nih.gov/pubmed/30979799 http://dx.doi.org/10.1083/jcb.201804101 |
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