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ATG2 transports lipids to promote autophagosome biogenesis

During macroautophagic stress, autophagosomes can be produced continuously and in high numbers. Many different organelles have been reported as potential donor membranes for this sustained autophagosome growth, but specific machinery to support the delivery of lipid to the growing autophagosome memb...

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Detalles Bibliográficos
Autores principales: Valverde, Diana P., Yu, Shenliang, Boggavarapu, Venkata, Kumar, Nikit, Lees, Joshua A., Walz, Thomas, Reinisch, Karin M., Melia, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548141/
https://www.ncbi.nlm.nih.gov/pubmed/30952800
http://dx.doi.org/10.1083/jcb.201811139