Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

Genotype imputation of the human leukocyte antigen (HLA) region is a cost-effective means to infer classical HLA alleles from inexpensive and dense SNP array data. In the research setting, imputation helps avoid costs for wet lab-based HLA typing and thus renders association analyses of the HLA in l...

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Detalles Bibliográficos
Autores principales: Degenhardt, Frauke, Wendorff, Mareike, Wittig, Michael, Ellinghaus, Eva, Datta, Lisa W, Schembri, John, Ng, Siew C, Rosati, Elisa, Hübenthal, Matthias, Ellinghaus, David, Jung, Eun Suk, Lieb, Wolfgang, Abedian, Shifteh, Malekzadeh, Reza, Cheon, Jae Hee, Ellul, Pierre, Sood, Ajit, Midha, Vandana, Thelma, B K, Wong, Sunny H, Schreiber, Stefan, Yamazaki, Keiko, Kubo, Michiaki, Boucher, Gabrielle, Rioux, John D, Lenz, Tobias L, Brant, Steven R, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Bioinformatics Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548229/
https://www.ncbi.nlm.nih.gov/pubmed/30590525
http://dx.doi.org/10.1093/hmg/ddy443

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